Autostrada del Sole A1, take exit Firenze Impruneta, proceed towards Firenze centro for about 5 kms. Proceed through Porta Romana to enter the centre of the city.
After driving all along Via Romana and proceeding along Via Maggio, turn left just before the bridge of Lungarno Guicciardini and continue straight towards the traffic light. At the traffic lights, turn right and cross the Ponte alla Carraia bridge. At the traffic lights, go straight into Via del Moro and drive to its end, then turn right into Via del Sole and proceed straight to the traffic light. Continue straight along Via degli Strozzi. Hotel Pendini is 200 m ahead, on the left, before Piazza della Repubblica. The hotel has a special agreement with a garage nearby, with pick-up and delivery services.
From the Firenze Santa Maria Novella train station you can take a taxi or reach the hotel on foot by walking towards the Cathedral, a ten minute walk.
The nearest airport is the Florence airport, which has daily flights to all the European capitals. It is some 5 kms from the city centre and there is a shuttle bus that will take you to the square in front of the main train station.
The centre of the city is 5 kms away and can be reached by bus or with a taxi in about 20 minutes.
The Pisa airport is 80 kms from Florence and can be reached over the motorway, by train or even a convenient shuttle bus that connects the central train station of Florence directly to the Pisa Galileo Galilei airport.